摘要: A class of novel platinum(II) complexes with 2-methyl-2-substituted phenoxypropanoic acids as leaving ligands were designed and synthesized.All complexes were characterized by IR,1H NMR and ESI-MS spectra.The in vitro antiproliferative activities were tested by MTT assay against three human cancer cell lines,indicating that the complexes showed selective cytotoxicity to human gastric cancer cell lines (SGC-7901) with only weak antiproliferative activities were observed against human hepatocellular carcinoma cell line (HepG2) and human non-small cell lung cancer cell line (A549).