水杨梅根的化学成分

张磊; 高颖; 蒋云涛; 阮善明; 沈敏鹤; 汪豪

doi:10.11665/j.issn.1000-5048.20150507

水杨梅根的化学成分

1.
中国药科大学天然药物化学教研室&天然药物活性组分与药效国家重点实验
2.
浙江中医药大学附属第一医院

基金项目: 国家自然科学基金资助项目(No.81172955)

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- 刊出日期: 2015-10-24

Chemical constituents of Adina rubella

摘要

摘要: 采用硅胶、ODS等柱色谱方法对水杨梅Adina rubella的干燥根的化学成分进行分离纯化，通过NMR，MS等波谱技术鉴定化合物结构，分离鉴定了12个化合物。分别为:5，7-二羟基-2-甲基色原酮-7-O-β-D-葡萄糖苷( 1 )，东莨菪苷( 2 )，(+)-lyoniresinol-3a-O-β-D-glucopyranoside( 3 )，(6S，7R，8R)-7a-［(β-D-glucopyranosyl)oxy］ lyoniresinol( 4 )，harman-3-carboxylic acid( 5 )，lyaloside( 6 )，3-oxoquinovid acid( 7 )，齐墩果酸( 8 )，3-acetyl oleanolic acid( 9 )，quinovic acid 3-O-β-D-glucopyranosyl-28-O-β-L-rhamnopyranosyl ester( 10 )，quinovic acid 3-O-β-D-glucopyranosiyl-28-O-β-D-glucopyranosyl ester( 11 )，pyrocincholic acid 3-O-α-L-rhamnopyranosyl-28-［β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl］ ester( 12 )。其中化合物 3 ， 4 ， 6 ， 8~10 均为首次从该植物中分离得到。
- 茜草科 /
- 水杨梅 /
- 化学成分 /
- 分离 /
- 鉴定
Abstract: From the ethanol extract of Adina rubella, twelve compounds were isolated by silica gel and ODS column chromatography. Their structures were identified by spectroscopic analysis as: 5, 7-dihydroxy-2-methylchromone-7-O-β-D-glucopyranoside( 1 ), scopolin( 2 ), (+)-lyoniresinol-3a-O-β-D-glucopyranoside( 3 ), (6S, 7R, 8R)-7a-［(β-D-glucopyranosyl)oxy］ lyoniresinol( 4 ), harman-3-carboxylic acid( 5 ), lyaloside( 6 ), 3-oxoquinovid acid( 7 ), oleanolic acid( 8 ), 3-acetyl oleanolic acid( 9 ), quinovic acid 3-O-β-D-glucopyranosyl-28-O-β-L-rhamnopyranosyl ester( 10 ), quinovic acid 3-O-β-D-glucopyranosiyl-28-O-β-D-glucopyranosyl ester( 11 )and pyrocincholic acid 3-O-α-L-rhamnopyranosyl-28-［β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl］ ester( 12 ). Compounds 3, 4, 6, 8-10 were isolated from this plant for the first time.
- Rubiaceae /
- Adina rubella /
- chemical constituents /
- isolation /
- identification

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参考文献(13)

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文章访问数: 1651
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水杨梅根的化学成分

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出版历程

Chemical constituents of Adina rubella

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出版历程

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