| [1] |
Surprenant A,North RA.Signaling at purinergic P2X receptors[J].Annu Rev Physiol,2009,71:333-359.
|
| [2] |
Von Kügelgen I,Harden TK.Molecular pharmacology,physiology,and structure of the P2Y receptors[J].Adv Pharmacol,2011,61:373-415.
|
| [3] |
Dal Ben D, Buccioni M, Lambertucci C, et al. Purinergic P2X receptors:structural models and analysis of ligand-target interaction[J].Eur J Med Chem,2015,89:561-580.
|
| [4] |
Surprenant A,Rassendren F,Kawashima E,et al.The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor(P2X7)[J].Science,1996,272(5262):735-738.
|
| [5] |
Rassendren F,Buell GN,Virginio C,et al.The permeabilizing ATP receptor,P2X7.Cloning and expression of a human cDNA[J].J Biol Chem,1997,272(9):5482-5486.
|
| [6] |
Costa-Junior HM,Sarmento Vieira F,Coutinho-Silva R.C terminus of the P2X7 receptor:treasure hunting[J].Purinergic Signal,2011,7(1):7-19.
|
| [7] |
North RA.Molecular physiology of P2X receptors[J].Physiol Rev,2002,82(4):1013-1067.
|
| [8] |
Di Virgilio F,Chiozzi P,Ferrari D,et al.Nucleotide receptors:an emerging family of regulatory molecules in blood cells[J].Blood,2001,97(3):587-600.
|
| [9] |
Kaczmarek-Hajek K,Lorinczi E,Hausmann R,et al.Molecular and functional properties of P2X receptors - recent progress and persisting challenges[J].Purinergic Signal,2012,8(3):375-417.
|
| [10] |
Skaper SD.Ion channels on microglia:therapeutic targets for neuroprotection[J].CNS Neurol Disord Drug Targets,2011,10(1):44-56.
|
| [11] |
Arulkumaran N,Unwin RJ,Tam FW.A potential therapeutic role for P2X7 receptor(P2X7R)antagonists in the treatment of inflammatory diseases[J].Expert Opin Investig Drugs,2011,20(7):897-915.
|
| [12] |
Birch RE,Schwiebert M,Peppiatt-Wildman CM,et al.Emerging key roles for P2X receptors in the kidney[J].Front Physiol,2013,4:262.
|
| [13] |
Solini A,Usuelli V,Fiorina P.The dark side of extracellular ATP in kidney diseases[J].J Am Soc Nephrol,2015.26(5):1007-1016.
|
| [14] |
Collo G,Neidhart S,Kawashima E,et al.Tissue distribution of the P2X7 receptor[J].Neuropharmacology,1997,36(9):1277-1283.
|
| [15] |
Ji X,Naito Y,Weng H,et al.P2X7 deficiency attenuates hypertension and renal injury in deoxycorticosterone acetate-salt hypertension[J].Am J Physiol Renal Physiol,2012,303(8):F1207-1215.
|
| [16] |
Arulkumaran N,Turner CM,Sixma ML,et al.Purinergic signaling in inflammatory renal disease[J].Front Physiol,2013,4:194.
|
| [17] |
Turner CM,Arulkumaran N,Singer M,et al.Is the inflammasome a potential therapeutic target in renal disease[J]? BMC Nephrology,2014,15:21.
|
| [18] |
Burnstock G,Nistri A,Khakh BS,et al.ATP-gated P2X receptors in health and disease[J].Front Cell Neurosci,2014,8:204.
|
| [19] |
Burnstock G.Purinergic signalling in the reproductive system in health and disease[J].Purinergic Signal,2014,10(1):157-187.
|
| [20] |
Guo C,Masin M,Qureshi OS,et al.Evidence for functional P2X4/P2X7 heteromeric receptors[J].Mol Pharmacol,2007,72(6):1447-1456.
|
| [21] |
Menzies RI,Unwin RJ,Dash RK,et al.Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats[J].Front Physiol,2013,4:305.
|
| [22] |
Booth JW,Tam FW,Unwin RJ.P2 purinoceptors:renal pathophysiology and therapeutic potential[J].Clin Nephrol,2012,78(2):154-163.
|
| [23] |
Ferrari D,Pizzirani C,Adinolfi E,et al.The P2X7 receptor:a key player in IL-1 processing and release[J].J Immunol,2006,176(7):3877-3883.
|
| [24] |
Jacobson KA,Jarvis MF,Williams M.Purine and pyrimidine(P2)receptors as drug targets[J].J Med Chem,2002,45(19):4057-4093.
|
| [25] |
Gunosewoyo H,Kassiou M.P2X purinergic receptor ligands:recently patented compounds[J].Expert Opin Ther Pat,2010,20(5):625-646.
|
| [26] |
North RA,Jarvis MF.P2X receptors as drug targets[J].Mol Pharmacol,2013,83(4):759-769.
|
| [27] |
Di Virgilio F.Novel data point to a broader mechanism of action of oxidized ATP:the P2X7 receptor is not the only target[J].Br J Pharmacol,2003,140(3):441-443.
|
| [28] |
Donnelly-Roberts DL,Namovic MT,Han P,et al.Mammalian P2X7 receptor pharmacology:comparison of recombinant mouse,rat and human P2X7 receptors[J].Br J Pharmacol,2009,157(7):1203-1214.
|
| [29] |
Donnelly-Roberts DL,Jarvis MF.Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states[J].Br J Pharmacol,2007,151(5):571-579.
|
| [30] |
Nelson DW,Gregg RJ,Kort ME,et al.Structure-activity relationship studies on a series of novel,substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists[J].J Med Chem,2006,49(12):3659-3666.
|
| [31] |
Honore P,Donnelly-Roberts D,Namovic MT,et al.A-740003[N-(1-{[(cyanoimino)(5-quinolinylamino)methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide],a novel and selective P2X7 receptor antagonist,dose-dependently reduces neuropathic pain in the rat[J].J Pharmacol Exp Ther,2006,319(3):1376-1385.
|
| [32] |
Turner CM,Tam FW,Lai PC,et al.Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in experimental and human glomerulonephritis[J].Nephrol Dial Transplant,2007,22(2):386-395.
|
| [33] |
Vonend O,Turner CM,Chan CM,et al.Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models[J].Kidney Int,2004,66(1):157-166.
|
| [34] |
Ji X,Naito Y,Hirokawa G,et al.P2X(7)receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats[J].Hypertens Res,2012,35(2):173-179.
|
| [35] |
Xu H,Liang SD.Effect of P2X7 receptor on inflammatory diseases and its mechanism[J].Acta Physiol Sinica(生理学报),2013,65(2):244-252.
|
| [36] |
Solini A,Menini S,Rossi C,et al.The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet:possible role of NLRP3 inflammasome activation[J].J Pathol,2013,231(3):342-353.
|
| [37] |
Taylor SR,Turner CM,Elliott JI,et al.P2X7 deficiency attenuates renal injury in experimental glomerulonephritis[J].J Am Soc Nephrol,2009,20(6):1275-1281.
|
| [38] |
Zhao J,Wang H,Dai C,et al.P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/caspase 1 pathway[J].Arthritis Rheum,2013,65(12):3176-3185.
|
| [39] |
Goncalves RG,Gabrich L,Rosario A Jr,et al.The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice[J].Kidney Int,2006,70(9):1599-1606.
|
| [40] |
Yan Y,Bai J,Zhou X,et al.P2X7 receptor inhibition protects against ischemic acute kidney injury in mice[J].Am J Physiol Cell Physiol,2015,308(6):C463-472.
|
| [41] |
Menzies RI, Unwin RJ, Bailey MA. Renal P2 receptors and hypertension[J].Acta Physiol(Oxf),2015,213(1):232-241.
|
| [42] |
Ponnusamy M,Ma L,Gong R,et al.P2X7 receptors mediate deleterious renal epithelial-fibroblast cross talk[J].Am J Physiol Renal Physiol,2011,300(1):F62-70.
|
| [43] |
Harada H,Chan CM,Loesch A,et al.Induction of proliferation and apoptotic cell death via P2Y and P2X receptors,respectively,in rat glomerular mesangial cells[J].Kidney Int,2000,57(3):949-958.
|
| [44] |
Schwiebert EM,Kishore BK.Extracellular nucleotide signaling along the renal epithelium[J].Am J Physiol Renal Physiol,2001,280(6):F945-963.
|
| [45] |
Guan Z,Fellner RC,Van Beusecum J,et al.P2 receptors in renal autoregulation[J].Curr Vasc Pharmacol,2014,12(6):818-828.
|
| [46] |
Burnstock G,Ralevic V.Purinergic signaling and blood vessels in health and disease[J].Pharmacol Rev,2014,66(1):102-192.
|
| [47] |
Wiley JS,Sluyter R,Gu BJ,et al.The human P2X7 receptor and its role in innate immunity[J].Tissue Antigens,2011,78(5):321-332.
|
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