[1] |
Fulda S,Galluzzi L,Kroemer G.Targeting mitochondria for cancer therapy[J].Nat Rev Drug Discov,2010,9(6):447-464.
|
[2] |
Marrache S,Dhar S.Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics[J].Proc Natl Acad Sci U S A,2012,109(40):16288-16293.
|
[3] |
Di Cosimo S,Ferretti G,Papaldo P,et al.Lonidamine:efficacy and safety in clinical trials for the treatment of solid tumors[J].Drugs Today(Barc),2003,39(3):157-174.
|
[4] |
Li N,Zhang CX,Wang XX,et al.Development of targeting lonidamine liposomes that circumvent drug-resistant cancer by acting on mitochondrial signaling pathways[J].Biomaterials,2013,34(13):3366-3380.
|
[5] |
Ringsdorf H.Structure and properties of pharmacologically active polymers[C].J Polym Sci Symp,1975,51(1):135-153.
|
[6] |
Hoste K,De Winne K,Schacht E.Polymeric prodrugs[J].Int J Pharm,2004,277(1):119-131.
|
[7] |
Cuchelkar V,Kopecková P,Kopecek J.Novel HPMA copolymer-bound constructs for combined tumor and mitochondrial targeting[J].Mol Pharm,2008,5(5):776-786.
|
[8] |
Wang M,Hu H,Sun Y,et al.A pH-sensitive gene delivery system based on folic acid-PEG-chitosan-PAMAM-plasmid DNA complexes for cancer cell targeting[J].Biomaterials,2013,34(38):10120-10132.
|
[9] |
Roy K,Ghosn B,Kasturi SP.Enhancing polysaccharide-mediated delivery of nucleic acids through functionalization with secondary and tertiary amines[J].Curr Top Med Chem,2008,8(4):331-340.
|
[10] |
Nel AE,Mödler L,Velegol D,et al.Understanding biophysicochemical interactions at the nano-bio interface[J].Nat Mater,2009,8(7):543-557.
|
[11] |
Mo R,Sun Q,Xue J,et al.Multistage pH-responsive liposomes for mitochondrial-targeted anticancer drug delivery[J].Adv Mater,2012,24(27):3659-3665.
|
[12] |
Duncan R,Vicent MJ.Polymer therapeutics-prospects for 21st century:the end of the beginning[J].Adv Drug Deliv Rev,2013,65(1):60-70.
|
[13] |
Hu X,Hu J,Tian J,et al.Polyprodrug amphiphiles:hierarchical assemblies for shape-regulated cellular internalization,trafficking,and drug delivery[J].J Am Chem Soc,2013,135(46):17617-17629.
|
[14] |
Jiang HL,Kim YK,Arote R,et al.Chitosan-graft-polyethylenimine as a gene carrier[J].J Control Release,2007,117(2):273-280.
|
[15] |
Kunath K,von Harpe A,Fischer D,et al.Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery:comparison of physicochemical properties,transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine[J].J Control Release,2003,89(1):113-125.
|
[16] |
Hu Q,Gao M,Feng G,et al.Mitochondria-targeted cancer therapy using a light-up probe with aggregation-induced-emission characteristics[J].Angew Chem Int Edit,2014,53(51):14225-14229.
|
[17] |
Silvestrini B,Palazzo G,De Gregorio M.Lonidamine and related compounds[J].Prog Med Chem,1984,21:111-135.
|
[18] |
Georg IG,Tash JS,Chakrasali R,et al.Lonidamine analogues and treatment of polycystic kidney disease:US,8362031[P].2013-01-29.
|