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功能化氧化石墨烯作为药物载体材料的研究进展

王晨, 许军, 刘燕华, 王增涛, 胡越, 田太平, 易梦娟

王晨, 许军, 刘燕华, 王增涛, 胡越, 田太平, 易梦娟. 功能化氧化石墨烯作为药物载体材料的研究进展[J]. 中国药科大学学报, 2017, 48(1): 117-124. DOI: 10.11665/j.issn.1000-5048.20170118
引用本文: 王晨, 许军, 刘燕华, 王增涛, 胡越, 田太平, 易梦娟. 功能化氧化石墨烯作为药物载体材料的研究进展[J]. 中国药科大学学报, 2017, 48(1): 117-124. DOI: 10.11665/j.issn.1000-5048.20170118
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WANG Chen, XU Jun, LIU Yanhua, WANG Zengtao, HU Yue, TIAN Taiping, YI Mengjuan. Research progress on functionalized graphene oxide as drug carriers[J]. Journal of China Pharmaceutical University, 2017, 48(1): 117-124. DOI: 10.11665/j.issn.1000-5048.20170118
Citation: WANG Chen, XU Jun, LIU Yanhua, WANG Zengtao, HU Yue, TIAN Taiping, YI Mengjuan. Research progress on functionalized graphene oxide as drug carriers[J]. Journal of China Pharmaceutical University, 2017, 48(1): 117-124. DOI: 10.11665/j.issn.1000-5048.20170118
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功能化氧化石墨烯作为药物载体材料的研究进展

  • 江西中医药大学药物化学教研室

基金项目: 江西省卫生计生委中医药科研计划资助项目(No.2014B002)

Research progress on functionalized graphene oxide as drug carriers

摘要

    摘要
  • 摘要: 功能化氧化石墨烯基于石墨烯的结构改造得到，具有良好的水溶性、生物相容性、较高的载药率以及易于修饰等优点，在国内外引起广泛的关注。本文综述了氧化石墨烯的表面修饰，以及它作为药物递送载体在抗肿瘤、抗菌、高血压治疗、基因治疗以及生物安全性评价等方面的应用，为其在生物医药领域的应用提供新方法和新思路。
    Abstract: Functionalized graphene oxide is prepared based on graphene. It has attracted great interest from all over the world due to its good solubility, biocompatibility, high loading rate, and easy modification. This paper summarizes the surface modification of graphene oxide, and its applications on anti-tumor, antibacteria, anti-hypertension, gene therapy and biosafety as a drug carrier, providing new methods and ideas in the biomedical field.
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    • 参考文献(47)
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  • 刊出日期:  2017-02-24

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