Abstract: Injections, tablets and solution of baicalin were given to each normal healthyman for the study of their absorption. The baicalin in urine was separated by ch-romatography and determined by UV spectrophotometric method. The pharmacokinetic data were fitted by nonlinear least square method with pocket-computer. The result showed that the rate peak value of baicalin injection appeared in urine at 0.4hr (Bioavailability : 89.3%), while that of tablets or solution was between 7.5-16.5 hrs ( Bioavailability: 22-36%) . The mean half-life Of baicalin injection ( 1M ) was 0.62 hr. It is eliminated rapidly and thus the dose of intramuscular injection given once a day was unreasonable.