双波长和三波长分光光度法测定盐酸普鲁卡因的含量

DUAL WAVELENGTH SPECTROPHOTOMETRY AND THREE WAVELENGTH SPECTROPHOTOMETRY OF PROCAINE HYDROCHLORIDE

摘要: 本文用双波长和三波长分光光度法在对氨基苯甲酸存在下,不经分离直接测定盐酸普鲁卡因的含量。前法测得平均回收率为99.86％±0.35％,后法测得平均回收率为99.51％±0.46％。
- 双波长分光光度法 /
- 三波长分光光度法 /
- 盐酸普鲁卡因
Abstract: An injection sample containing procaine hydrochloride (I) and p-aminobenzoic acid (Ⅱ) was diluted with pH 10 buffer soln. and determined with 751G spectrophotometer at 287,284.5nm in dual wavelength spectrophotometry or at 264,287,315 nm in three wavelength spectrophotometry for the determination of Ⅰ. Absorbance showed a linear dependence on the concentration of I in the range of 3—11 μg/ml. The mean recoveries of two methods were found to be 99.68±0.35% and 99.51％±0.46％, respectively. The results obtained from four batches of samples showed no significant difference between the two methods at 95% confidence level.
- D(?)al wavelength spectrophotometry /
- Three wavelength spectrc-photometry /
- Procaine hydrochloride