紫外分光光度法测定苯氮嘌呤酮片的含量

DETERMINATION OF PHENYLAZAPURINONE IN TABLETS BY UV SPECTROPHOTOMETRY

摘要: 苯氮嘌呤酮(邻苯氮嘌呤酮三乙醇胺盐)是一个较新的抗过敏药,但未见有含量测定方法报道,为此,我们根据苯氮嘌呤酮的理化性质,设计了含量测定方法。本品是由甲基黄嘌呤酮的结构改造而成,其结构为:

Abstract: The UV spectrophotometry was used for the determination of phenyl- azapurinone in N/10 sodium hydroxide solution at 275 nm and the absorptivity is 458.6. The average recovery of phenylazapurinone was 99.8% with coefficient of variation 0.46%. This method