片剂生产中厢式干燥器生产能力的实验研究

EXPERIMENTAL STUDY ON PRODUCTIVE CAPACITY OF TRAY DRYER FOR TABLETS

摘要: 本文对片剂湿颗粒在厢式干燥器中的干燥过程进行了研究。在用正交设计安排试验判找各影响因素的相对大小后,对空气温度,颗粒床层厚度、颗粒堆积紧密程度及盘高的影响分别进行了研究,为预测可能达到的生产能力提供了依据。本试验虽是以本院药厂某片剂湿颗粒为样品,但其方法及结论对其它片剂生产也有一定的参考价值。

Abstract: A drying process of wet granules in tray dryer was studied.The factors in air temperature,thickness of bed layer,stack density and trayheight were studied individually using the design of orthogonal array todetermine the magnitude of influence during the