猴头多糖的提取分离、理化分析及生物活性的初步研究
ISOLATION,ANALYSIS AND BIOLOGICAL ACTIVITIES OF THE POLYSACCHARIDE OF HERICIUM ERINACAUS
-
摘要: 猴头菌Hericium erinacus(full.ex Fr)Pers菌丝体干粉以热水提取,除蛋白,透析,乙醇沉淀,得猴头多糖(HP),经UV-300紫外扫描,未发现有核酸和明显的蛋白质吸收峰。小鼠腹腔注射(2mg/只×7天),可明显提高小鼠腹腔巨噬细胞的吞噬能力,与对照组比较,吞噬指数提高4.5倍,吞噬百分率提高0.77倍。小鼠腹腔注射(2mg/只×7天),可促进溶血素生成,增加体液免疫的能力。另外,小鼠腹腔注射(2.88mg/只×8天),可明显对抗由环磷酰胺中毒所引起的白细胞下降,下降率仅为对照组的一半。Abstract: The polysaccharide(H)was isolated from the hyphae of ChineseHericium erinacaus.in mice,HP was found to enhance the phagocytosisof macrophage by intraperitoneal injection.The phagocytic index increas-ed by 4.5 times as compared with the control.HP promoted