炔睾醇对肝脏及免疫器官的作用
EFFECT OF DANAZOL ON THE LIVER AND IMMUNE ORGANS
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摘要: 炔睾醇具有抑制下丘脑—垂体—性腺轴的作用和抗雌激素、抗孕激素的作用。Eldrige等报道炔睾醇还有降低阉割动物血中促性腺激素作用。国外临床用于治疗子宫内膜异位症具有较好疗效,部分病例出现一过性SGPT升高。炔睾醇对实验动物肝脏及免疫器官的影响尚未见报道。作者对本院有机化学教研室利用国产原料研制的炔睾醇进行了这Abstract: Experiments showed that danazol did not affect the activity of SGPT and the structure of hepatic tissue in rats.It also had no effects on theight of thymus,spleen adrenal gland and total leucocyte count,but it couldincrease the weight of kidney when admin