女贞子及其成分齐墩果酸对环磷酰胺及乌拉坦引起染色体损伤的保护作用

PROTECTION OF FRUCTUS LIGUSTRI LUCIDI AND OLEANOLIC ACID ON THE CHROMOSOMAL DAMAGE INDUCED BY CYCLOPHOSPHAMIDE AND URETHAN

摘要: 女贞子(Fructus Ligustri Lucidi,FLL)是木犀科植物女贞Ligustrum lucidum Ait.成熟的果实,是中医常用的扶正药,具有滋阴、补肝肾作用。研究表明女贞子能多环节地影响机体的免疫功能,其水煎剂可抑制小鼠子宫颈癌,这与中医的“扶正祛邪”有相似之

Abstract: Protection effect of Fructus Ligustri Lucidi (FLL) and oleanolic acid on the chromosomal damage by counting the frequency of micronucleus in mouse hone-marrow was studied. Mice were given either FLL (decoction) 12.5, 25g/kg/d po 6d or oleanolic acid 50, 7