4-芳杂环胺甲基酚衍生物的体外抗血小板聚集活性
PLATELET ANTIAGGREGATING ACTIVITY (IN VITRO) OF SOME 4-HETERO-ARYLAMINOMETHYL-PHENOL DERIVATIVES
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摘要: 血小板体内聚集可使心肌微循环功能产生障碍,导致心律失常或心肌梗塞,血小板聚集在心脑血管疾病的发病机理中起着重要作用,因而对抗血小板聚集药物的研究日益引起人们Abstract: Many 4-hetero-arylamiaomethylphenol derivatives were syntheslzed. With an attempt to search for new potent platelet antiaggregating drugs, fifteen of them were tested for their antiaggregating activity. Some of the compounds can inhibit platelet aggregati