4-(2′-乙酰氧基苯甲酰基)-阿魏酸的合成和生物活性

摘要: 阿斯匹林(ASA)是环氧酶抑制剂。阿魏酸(Ferulic acid.FA)是当归中的活性成分之一,具有抑制血小板5-HT释放和阻抑静脉旁路血栓形成等作用,其机理与ASA的不同。文献报道ASA和FA联用可增强大鼠
- 阿斯匹林 /
- 阿魏酸 /
- 抗血小板聚集作用
Abstract: Since aspirin and ferulic acid both showed platelet antiagregating activity, the ester-4-(2'-acetoxybenzoyl)-ferulic acid was synthesized by means of condensation of aspirin and ferulic acid so as to reduce the irritation of aspirin on gastro-intestinal t
- Aspirin /
- Ferulic acid /
- Platelet antiaggregating activity