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氟胞嘧啶合成工艺的改进

IMPROVED METHOD FOR SYNTHESIS OF 5-FLUOROCYTOSINE (5-FC)

  • 摘要: 氟胞嘧啶(1,5-Fluorocytosine,简称5-Fc)系一抗深部真菌的有效药物,化学名为

     

    Abstract: A modified method for preparing 5-Fluorocytosine, a systemic antifungal agent. was described. The amination of 2-methyoxy-4-chloro-5-fluoropyrimidine was performed under normal pressure instead of high pressure as reported in literature. The process of th

     

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