非甾体抗炎药4（2—噻吩羰基）苯酚类化合物的抗炎活性

Anti-inflammatory Activity of New Non-steroidal Antiinflammatory Agent: Derivatives of 4-(2-Thiophene Carbonyl)-Phenol Compounds

摘要: 非甾体类抗炎药临床上用于治疗风湿性关节炎及其它胶原性疾病。国内外正不断地寻找新的化合物。我们曾发现氨甲基酚类化合物有较好的抗炎活性。一些含有4芳杂环苯
- 非甾体抗炎药 /
- 4-(2-噻吩羰基)苯酚类化合物 /
- Freund's完全佐剂 /
- 角叉菜胶 /
- 吲哚美辛
Abstract: Five derivatives of 4-(2-thiophene-carbonyl)-phenol compounds were tested for their anti-inflammatory activity, with substituents of -N-methylene-pyridine, -N-methylene-N'-methyl-piperazine, and -N-methylene-N'-p-fluoro-phenyl-piperazine on the 2 and 6 po
- Non-steroidal anti-inflammatory agent /
- 4-(2-thiophene-carbonyl)-phenol compounds /
- Freund's complete adjuvant /
- Carrageenin /
- Indomethacin