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非甾体抗炎药4(2—噻吩羰基)苯酚类化合物的抗炎活性

Anti-inflammatory Activity of New Non-steroidal Antiinflammatory Agent: Derivatives of 4-(2-Thiophene Carbonyl)-Phenol Compounds

  • 摘要: 非甾体类抗炎药临床上用于治疗风湿性关节炎及其它胶原性疾病。国内外正不断地寻找新的化合物。我们曾发现氨甲基酚类化合物有较好的抗炎活性。一些含有4芳杂环苯

     

    Abstract: Five derivatives of 4-(2-thiophene-carbonyl)-phenol compounds were tested for their anti-inflammatory activity, with substituents of -N-methylene-pyridine, -N-methylene-N'-methyl-piperazine, and -N-methylene-N'-p-fluoro-phenyl-piperazine on the 2 and 6 po

     

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