四环素荧光法区分大鼠梗塞心脏中梗塞区、灌流区及非梗塞区
Determination of the Infarcted, Risk and Non-infarcted Zone of the Infarcted Rat Heart by Tetracycline Fluoroscent Staining
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摘要: 大鼠iv四环素30 min后,按荧光强度将梗塞心脏(缺血60 min—再灌23 h)分为无荧光区(梗塞区),强荧光区(灌流区)和弱荧光区(非梗塞区)。电镜及SOD测定证实区分合理,与Evans蓝—红四氮唑染色配对比较,结果一致。普萘洛尔能显著缩小无荧光区及增加强荧光区的重量。Abstract: The infarcted rat heart caused by 60 min ischemia followed by reperfusion for 23 h was delineated by the potency of fluorescence, after iv injecting 10% tetracycline 1 ml, into the following three zones: the infarcted zone (the absence of fluorescence), t