2位双取代苯骈吡喃酮与盐酸羟胺反应产物的研究

Study on the Reaction of 2-Bisubstituted Benzopyranone and Hydroxylamine Hydrochloride

摘要: 苯骈吡喃类钾通道启开剂目前是降压药研究和开发的热点。在合成一系列钾通道启开剂苯骈吡喃化合物的中间体苯骈吡喃酮肟时,我们用2,2-二甲基-6-硝基-2,

Abstract: It is reported that 2-monosubstituted benzopyranone oximes may rearrange to isoxazoline under acid condition, and at the same time the rearrangement will not take place in anhydrous ethanol and a small amount of pyridine. However, 2-bisubstituted benzopyr