复方布洛芬片的高效液相色谱分析
Determination of Ibuprofen and Pseudoephedrine in Compound Ibuprofen Tablet by HPLC
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摘要: 对复方布洛芬片中布洛芬和盐酸伪麻黄碱的高效液相色谱分析进行了研究,考察了流动相pH、组成等对分离的影响情况。以双氯灭痛为内标,检测波长为215.0nm,在所测浓度范围内,峰面积与被测物浓度的线性关系良好。布洛芬和盐酸伪麻黄碱的回收率分别为99.37%和99.94%,RSD<2.2%(n=5)。Abstract: A sensitive and simplified high performance liquid chromatographic procedure has been developed to determine ibuprofen and pseudoephedrine hydrochloride in compound ibuprofen tablet. Diclofenac sodium was used as internal standard and the detection wavele