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氮酮对葛缕酮透皮速率的影响

Effect of Azone on the Permeability of Carvone Through Excised Rat Skin In Vitro

  • 摘要: 利用离体大鼠皮肤为渗透屏障,研究了祛寒理气涂膜剂中葛缕酮在促吸剂氮酮作用下的透皮效果。用气相色谱法测定葛缕酮。氮酮的促吸作用在一定浓度范围内随着浓度增加而增加,2%的氮酮促吸效果最佳,稳态流量为1701.0μg·cm-2。

     

    Abstract: The effect of penetration enhancers on the pormeability of carvone from Quhanliqi smeared film through excised rat skin in vitro was examined using the Franz diffusion cell and the normal saline as receptor medium.The results showed that the penetration r

     

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