甲砜霉素甘氨酸酯盐酸盐合成产品的RP－HPLC优化分离与定量分析

Optimized Separation and Assay of Thiamphenicol Glycinate Hydrochloride Synthetic Product by Reversed-Phase HPLC

摘要: 本文采用灰色均匀设计对甲砜霉素甘氨酸酯盐酸盐合成产品进行了ＲＰ－ＨＰＬＣ优化分离，并以烟酰胺为内标建立了同时测定甲砜霉素与甲砜霉素甘氨酸酯盐酸盐的定量分析方法。

Abstract: Thiamphenicof glycinate hydrochloride sythetic product was separated optimally by RPHPLC based on grey uniform design,and an assay procedure was established for the simultaneous determination of thiamphenicol and thiamphenicol glycinate hydrochloride usin