雷公藤巴布剂对大鼠佐剂性关节炎的治疗作用

Effect of Tripterygium wilfordii PAP Patcher(TWPP) on Adjuvant Arthritis in Rats

摘要: 用Ｆｒｅｕｎｄ＇ｓ完全佐剂诱发大鼠产生佐剂性关节炎（ＡＡ），以继发性反应左后足跖的肿胀度、前肢、耳和尾部病变的发生率以及免疫器官胸腺、脾脏指数为指标，观察了雷公藤巴布剂对大鼠ＡＡ的治疗作用。结果表明，雷公藤巴布剂对ＡＡ有明显的治疗作用，其效果较等剂量口服的片剂及浸膏剂显著。

Abstract: Adjuvant arthritis in rats was induced by Freund's complete adjuvant.The secondary reactions including swelling degree in left-hind feet,changes of front legs,ears and tail,and thymus and spleen indexes were oberved.The results showed significant effect o