原料药乙酰水杨酸中水杨酸的流动注射光度分析法
Determination of Salicylic Acid in Bulk Pharmaceuticals of Acetyl-Salicylic Acid by Flow Injection Spectrophotometry
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摘要: 基于水杨酸在ｐＨ２的盐酸介质中与Ｆｅ＾３＋生成紫色络合物，在５２０ｎｍ处有强吸收，而乙酰水杨酸无干扰的原理，建立了流动注射光度法测定原料药乙酰水杨酸中杂质水杨酸的含量，方法快速、简便。在０．０１￣０．２０ｍｇ／ｍｌ浓度范围内线性关系良好，方法回收率为１０１．５％。Abstract: Salicylic acid reacts with Fe3 in pH 2 hydrochloric acid medium to form a violet complex,showing a strong atherption at 520 nm. A flow injection spectrophotometry for the determination of satlicylic acid in bulk pharmaceutical of acetyl salicylic acid is
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