D—氨基葡萄糖盐酸盐的制备研究

Preparation of D Glucosamine Hydrochloride

摘要: 从龙虾壳制备的甲壳素，经盐酸水解得Ｄ－氨基葡萄糖盐酸盐，收率＞５０％，纯度＞９８．７％。水解条件考察表明，以１２ｍｏｌ／ＬＨＣｌ水解２．５～３ｈ效果最佳。
- 甲壳素 /
- D-氨基葡萄糖盐酸盐 /
- 薄层层析
Abstract: Chitin was prepared from fresh and dry lobster shell with average yield of 4.1% and 18.2% respectively. D-Glucosamine hydrochloride(D-GclN•HCl) was made from chitin with average yield of 53.9% and the purity of 98.6% . The effect of concentration of hydrochloric acid, and its hydrolytic time on the reaction was invesitgated at the same time. The product was confirmed by TLC,IR,MS and elementary analysis. The compound has two mp of 197.195℃ and 217.857℃. Δ H value is 666.481J/g. The[α]27D is +72.18°.
- Chitin /
- D-GlcN•HCl /
- TLC