噻吩骈嘧啶二酮类化合物的合成及其强心活性
Synthesis and Cardiac Activity of Thieno Pyrimidine 2,4 Dione Derivatives
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摘要: 设计合成了12个噻吩骈[3,4-d]嘧啶-2,4-二酮类化合物,其结构经红外光谱、核磁共振光谱、质谱证实。初筛试验表明,大部分化合物具有强心活性,其中化合物TPD12的活性最好Abstract: In search of new cardiac compounds twelve derivatives of thieno pyrimidine 2,4 dione were designed and synthesized Their structures were confirmed by spectroscopic elucidation In preliminary biological testes, some of the compounds showed the varie