马鞭草抗早孕作用的动物实验研究
The Animal Study of Verbena Officinalis on Anti early preg nancy
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摘要: 给早孕小鼠灌服马鞭草提取液,光镜观察细胞生长情况,细胞的变化及微血管分布情况。观察其对早孕小鼠子宫、胎盘、胎仔的影响,并作形态描述。实验表明:马鞭草能明显抑制胚胎生长使其固缩死亡,胚胎重量0 .129 ±0 .075 g ,与空白对照组比较有显著差异( P< 0 .05) ;胎仔长0 .32 ±0 .14 cm ,与空白对照组比较有极显著差异( P< 0 .01) ,与米非司酮组比较无显著差异( P> 0 .05) 。光镜显示:胎盘滋养层细胞退变凋亡,可见核固缩,染色质向细胞核膜下集聚。光镜下采用NYD1000 型图像分析Q 系统测定胎盘组织微血管分布面积,明显小于空白对照组( P< 0 .01) ,与米非司酮组比较无显著差异( P> 0 .05) 。结果表明马鞭草的抗早孕可能与其抗孕酮作用有关。Abstract: By giving the extract of \%Verbena Officinalis\% to pregnant mice, in the experiment its effects on decription of embryo, growth of cells, change of cell organs and distribution of microvessels were observed. It showed that \%Verbena Officinalis\% could i