HPLC法测定复方美沙芬缓释片的释放度和含量
Determination of in Vitro Release and Content of Dextrome thorphan Hydrobromide and Pseudoephedrine Hydrochloride Sustained-Release Tablets by HPLC
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摘要: 采用HPLC法测定复方美沙芬缓释片释放度和含量。该法采用YWG-C18色谱柱,以乙腈-醋酸钠溶液-高氨酸-三乙胺（40：60：0.5：0.1）为流动相,能同时测定制剂中伪麻黄碱和氢溴酸右美沙芬,精密度好,峰面积与浓度呈良好线性关系,回收率约100％,RSD＜1.5％。Abstract: Determination of release and content of compound dextromethorphan sustuined release tablets by HPLC was established. This stationary phase was YWG-C18, the mobile phase was composed of the mixture of acetonitrile and CH3COONa buffer. This condition for an
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