盐酸丁螺环酮的多晶型研究

Investigation of Buspirone Hydrochloride Polymorphs

摘要: 制备了多晶型盐酸丁螺环酮 ,通过 X-射线粉末衍射、红外光谱、差热分析等方法 ,确定盐酸丁螺环酮存在 3种晶型 ,即晶型 A(无水乙醇结晶物 )、晶型 B(氯仿结晶物 )和晶型 C(晶型 A、B的加热产物 ) ,并研究了不同晶型间的转变条件和转变规律

Abstract: The polymorphs of buspirone hydrochloride were prepared and characterized by means of X ray powder diffraction, IR and DSC. Buspirone hydrochloride was found to exist in three crystal forms, form A(crystal from absolute alcohol) ,form B (crystal from ch