非洛地平缓释胸囊的制备及其释药特性研究

Preparation and Release Properties of Felodipine Sustained-release Capsules

摘要: 选用颈珍基甲基纤维素为水凝胶型骨架材料、乙基纤维素为阻滞剂制备非洛地平缓释胶囊。通过考察其体外释放度，评价了该缓释胶囊的处方，结果表明，该制剂的体外释药行为符合Ｈｉｇｕｃｈｉ方程。

Abstract: Felodipine was formulated with some excipients to prepare sustained release capsules. The influence of HPMC with different viscosity and EC with different capacity on the drug release in vitro has been studied. The results showed that the release behavio