化学酶法制备D—苯甘氨酸

Chemoenzymatic Synthesis of D-Phenylglycine

摘要: 对化学酶法制备Ｄ－苯甘氨酸工艺进行了研究。利用荧光假单胞菌９８０６作为酶源，将ＤＬ－苯海因生物转化为Ｎ－氨基甲酰－Ｄ－苯甘氨酸，后者与亚硝酸钠反应生成Ｄ－苯甘氨酸，收率为４７．５％。

Abstract: D phenylglycine produced by chemoenzymatic synthesis was studied in details: N carbamyl D phenylglycine was biotransformated from DL phenylhydantoin while \%Pseudomonas fluorescence\% 9806 was used as enzyme source, and then D phenylglycine was synt