荆芥内酯类提取物对大鼠足跖汗腺及血液流变学的影响

Impact of Lactones of Schizonepeta Tenuifolia Briq. on Plantar Sweat Gland and Hemorrheology of Rats

摘要: 目的观察荆芥内酯类提取物对汗腺及血液流变学的影响。方法大鼠腹腔注射给药1h后，自踝关节处迅速取下双后足，10%甲醛溶液固定，对足跖部汗腺腺泡上皮细胞在光镜下作形态学观察。大鼠血（肝素抗凝）用于血液流变学测定。结果荆芥内酯类提取物能明显提高汗腺腺泡上皮细胞的空泡发生率，数密度和面密度，显著降低全血比粘度和红细胞的聚集性。结论荆芥内酯类提取物具有显著的发汗和改善血液流变学的作用。

Abstract: AIM To assess the impact of the lactones of Schizonepeta tenuifolia Briq. (LST) on plantar sweat gland and hemorrheology of rats. METHODS The double metapodia of the rats were cut immediatedly at the ankle joint at 1 h after intraperitoneal injection o