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绞股蓝的化学成分研究

Studies on Chemical Constituents of Gynostemma Pentaphyllum

  • 摘要: 目的:对葫芦科植物绞股蓝的抗肿瘤活性皂苷成分进行研究。方法:利用色谱的方法分离活性皂苷成分,利用波谱和化学方法鉴定各单体皂苷成分的化学结构。结果:从绞股蓝的地上部分离得到多个化合物,鉴定了其中5个皂苷成分的结构:3-0-β-D-吡喃葡萄糖基2α,3β,12β,20(S)-3羟基-达玛烷24-烯20-O-β-D-吡喃葡萄糖苷(1),GynosaponinTN-1(2),Gypenoside LXXⅦ(3),Gypenoside XLⅥ(4)和Gynseoside Rd(5),其中化合物1为新天然产物。

     

    Abstract: AIM:To isolate and identify the anticancer constituents of Gynostemma pentaphyllum . METHOD:Some chromatographic methods were applied to isolate pure saponins, whose structures were elucidated by using chemical and spectroscopic methods. RESULT:Compou

     

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