海洋软体动物提取物抗肿瘤活性研究进展
Advances in the study of antitumor activities of the marine mollusks extracts
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摘要: 海洋软体动物鲍鱼、海兔、乌贼、泥蚶、青蛤、贻贝、扇贝、文蛤、牡蛎、缢蛏等的提取物肽类、多肽、糖肽、糖蛋白、糖胺聚糖具有抗肿瘤、抗衰老、抗菌等作用。由于癌症患者长期化疗会损害重要脏器，而且会产生耐药性，影响其化疗效果。因此，寻找低毒、高效的新型抗肿瘤药物势在必行。目前对几种海洋软体动物药用活性正在研究中，本文对常见的海洋软体动物的抗肿瘤活性进行综述，为海洋抗肿瘤药物的研究开发提供参考。Abstract: The extracts of marine mollusks（Abalone，Aplysia，Sepia，Arcagranosa linnaeus，Cyclina sinensis，Mytilus coruscus，Chlamys farrei，Meretrix meretrix，Ostrea，Sinonovacula constricta and Solen gradis）classified as polysaccharides，proteins and peptides，possess the antitumor，anti-aging，and anti-bacterial activities.Cancer patients undergoing long-term chemotherapy usually suffer from the damage to vital organs，and resistances affecting the outcomes of chemotherapy.Therefore，it is imperative to search for anti-cancer drugs with low toxicity and high efficiency.At present，several marine mollusks are being studied.Summary on the antitumor activities of the marine mollusks extrats is presented，which might provide a basis for the development of marine anti-cancer drugs.
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Keywords:
- marine mollusks /
- marine drugs /
- antitumor
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