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甲壳素/壳聚糖及其衍生物与血液的相互作用

程沁园, 张家骊, 夏文水

程沁园, 张家骊, 夏文水. 甲壳素/壳聚糖及其衍生物与血液的相互作用[J]. 中国药科大学学报, 2011, 42(1): 92-96.
引用本文: 程沁园, 张家骊, 夏文水. 甲壳素/壳聚糖及其衍生物与血液的相互作用[J]. 中国药科大学学报, 2011, 42(1): 92-96.
CHENG Qin-yuan, ZHANG Jia-li, XIA Wen-shui. Interactions of chitin,chitosan and their derivatives with blood constitutes[J]. Journal of China Pharmaceutical University, 2011, 42(1): 92-96.
Citation: CHENG Qin-yuan, ZHANG Jia-li, XIA Wen-shui. Interactions of chitin,chitosan and their derivatives with blood constitutes[J]. Journal of China Pharmaceutical University, 2011, 42(1): 92-96.

甲壳素/壳聚糖及其衍生物与血液的相互作用

基金项目: 国家高技术研究发展计划(“八六三”计划)资助项目(No.2007AA091603);食品科学与技术国家重点实验室目标导向资助项目(No.SKLF-MB-200805);教育部长江学者与创新团队发展计划资助项目(No.0627);高等学校学科创新引智计划资助项目(111计划)(No.B07029)

Interactions of chitin,chitosan and their derivatives with blood constitutes

  • 摘要: 甲壳素/壳聚糖是来源丰富的天然有机物,具有多种生物活性且应用广泛。本文重点综述了甲壳素、壳聚糖及其衍生物的止血活性及作用机制的国内外研究进展,并列举了一些已市售或正在研制中的甲壳素/壳聚糖基止血敷料。此外,甲壳素/壳聚糖的特殊衍生物(如硫酸化衍生物)具有截然相反的抗凝血活性,因此亦对其抗凝血衍生物的研究近况进行了介绍。
    Abstract: Chitin and chitosan are natural organic matters with rich resources and wide applications due to their various bioactivities.In this paper,research progresses on the hemostasis activities and action mechanisms of chitin,chitosan,and their derivatives at home and abroad are summarized.Some hemostasis dressings based on chitin or chitosan are introduced.In addition,the derivatives such as sulfated derivatives showed the anticoagulant activity which contrary to chitin and chitosan,so their recent research developments are also presented..
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  • 刊出日期:  2011-02-24

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