Essential Effect of Stratum Corneum and Its Lipids on Permeability of Oestradiol through Human Skin
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Graphical Abstract
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Abstract
The effect of stratum corneum(SC) and its lipids in human skin permeation was assessed in ritro in a diffusion system, combined with the determination of partition coefficients. OE and 1, 8-CN were used as the model lipophUie drug and penetration enhancer
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