Synthesis, Analgesic Activity and Structure-Activity Relationship of 4-N-Cyclohexyl Analogs of Some Fentanyl Derivatives[J]. Journal of China Pharmaceutical University, 1993, (3): 139-144.
Citation:
Synthesis, Analgesic Activity and Structure-Activity Relationship of 4-N-Cyclohexyl Analogs of Some Fentanyl Derivatives[J]. Journal of China Pharmaceutical University, 1993, (3): 139-144.
Synthesis, Analgesic Activity and Structure-Activity Relationship of 4-N-Cyclohexyl Analogs of Some Fentanyl Derivatives[J]. Journal of China Pharmaceutical University, 1993, (3): 139-144.
Citation:
Synthesis, Analgesic Activity and Structure-Activity Relationship of 4-N-Cyclohexyl Analogs of Some Fentanyl Derivatives[J]. Journal of China Pharmaceutical University, 1993, (3): 139-144.
Synthesis, Analgesic Activity and Structure-Activity Relationship of 4-N-Cyclohexyl Analogs of Some Fentanyl Derivatives
The synthesis of 4-N-cyclohexyl analogs of fentanyl, cis-3-methylfentanyl and 4-acetyl fentanyl was reported. Results in mouse hot plate test showed that the substitution of 4-N-phenyl by cyclohexyl caused decrease of analgesic activity, and the degree of
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