Research on the Reaction Mechanism of Synthesis Ondansetron

Research on the Reaction Mechanism of Synthesis Ondansetron[J]. Journal of China Pharmaceutical University, 1999, (1): 3-4.

Citation:

Research on the Reaction Mechanism of Synthesis Ondansetron[J]. Journal of China Pharmaceutical University, 1999, (1): 3-4.

Citation:

Research on the Reaction Mechanism of Synthesis Ondansetron[J]. Journal of China Pharmaceutical University, 1999, (1): 3-4.

Abstract

HT 3 receptor antagonist ondansetron can be prepared directly from 9 methyl 1,2,3,9 tetrahydro 4H carbazol 4 one(2) by new technology of one pot reaction. Mannich reaction intermediate 1 hydroxymethyl 2 methyl imidazole(3) was synthesized an

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