Mechanism of TNF Related Apoptosis Inducing Ligand Inducing Apoptosis and Its Pharmaceutical Exploitation
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Abstract
TNF related apoptosis inducing ligand(TRAIL) belongs to TNF(tumor necrosis factor) superfamily. It's binding to death receptor (DR) initiate cellular signaling,and specially induces the apoptosis in tumor cells but not in normal tissue cells. So TRAIL see
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