Chemical constituents from Artemisia rupestris L.
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Graphical Abstract
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Abstract
From the ethanol extract of the aerial parts of Artemisia rupestris,sixteen compounds were isolated by repeated column chromatography with silica gel,Sephadex LH-20 and C18. Their structures were identified by spectroscopic techniques(1H NMR,13C NMR and so on) as:rupestonic acid( 1 ),12-hydroxy-4,11(13)-guaiadien- 3-one( 2 ),luteolin( 3 ),5,7-dihydroxy-3′,4′-dimethoxyflavone( 4 ),luteolin 7-O-β-D- glucoside( 5 ),luteolin 7-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranoside\( 6 ),linarin( 7 ),quercetin( 8 ),nevadensin( 9 ),gardenin D( 10 ),skimmin( 11 ),stigmasterol -3-O-β-D-glucopyranoside( 12 ),1,2-isopropylidene-α-D-glucopyranose( 13 ),tianshic acid( 14 ),β-sitosterol( 15 ) and daucosterol( 16 ). Among them,compounds 2,4,6,9,11-14 were isolated from this plant for the first time.
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