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Synthesis of Progesterone Receptor Antagonist ZK98299[J]. Journal of China Pharmaceutical University, 1992, (4): 209-212.
Citation: Synthesis of Progesterone Receptor Antagonist ZK98299[J]. Journal of China Pharmaceutical University, 1992, (4): 209-212.
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Synthesis of Progesterone Receptor Antagonist ZK98299

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  • Progesterone receptor antagonist ZK98299 (8b) and its C_(17)-iso-mer (8a) were synthesized from A~(4.9)-estradien-3,7-dione (1) via seven-step process in 4.7% total yield.
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