粉条儿菜化学成分的研究

基金项目: 国家“重大新药创制”科技重大专项基金资助项目(No.2011ZX09307-002-02)

Chemical constituents from Aletris spicata

摘要: 采用多种柱色谱方法对百合科粉条儿菜属植物粉条儿菜Aletris spicata(Thunb.)Franch.进行分离纯化，运用波谱学方法鉴定了10个化合物，分别为环石仙桃萜醇(cyclopholidonol， 1 )、白桦脂酸(betulinic acid， 2 )、熊果酸(ursolic acid， 3 )、13-表柏油酸(13-epicupressic acid， 4 )、5-羟基-3，7，4′-三甲氧基黄酮(5-hydroxy-3，7，4′-trimethoxyflavone， 5 )、二十二烷酸-1-甘油酯(2，3-dihydroxypropyl docosoate， 6 )、正十七烷醇(1-heptadecanol， 7 )、正二十四烷酸(lignoceric acid， 8 )、24，24-二甲基-环木菠萝烷-3-醇(cycloneolitsoln， 9 )和β-谷甾醇(β-sitosterol， 10 )。化合物 1~8 均为首次从该属植物中分离得到。
- 粉条儿菜 /
- 化学成分 /
- 三萜 /
- 结构鉴定
Abstract: Ten compounds were isolated and purified from the ethanol extract of Aletris spicata by various chromatographic methods. Their structures were identified as cyclopholidonol( 1 ), betulinic acid( 2 ), ursolic acid( 3 ), 13-epicupressic acid( 4 ), 5-hydroxy-3, 7, 4′-trimethoxyflavone( 5 ), 2, 3-dihydroxypropyl docosoate( 6 ), 1-heptadecanol( 7 ), lignoceric acid( 8 ), cycloneolitsol( 9 )and β-sitosterol( 10 ). Compounds 1-8 were isolated from genus Aletris for the first time.
- Aletris spicata /
- chemical constituents /
- triterpenoids /
- structural identification

[1]	Flora of China Commission.Flora of China:Vol.15(中国植物志:卷15)[M].Beijing:Science Press,1978:168-181.
[2]	The Editorial Committee of National Collection of Chinese Herbal Medicine.National Collection of Chinese Herbal Medicine(全国中草药汇编)[M].Beijing:People′s Medical Publishing House,1996:677-678.
[3]	Akira A,Fumio Y,Tameto O.Steroidal sapogenins of Aletris spicata(Thunb.)Franchet[J].Chem Pharm Bull,1971,19:2 409-2 411.
[4]	Hao Q,Li R,Yao Y,et al.C-glycosylflavone from Aletris spicata[J].Biochem Syst Ecol,2012,45:191-193.
[5]	Huang L,Pan J,Cao PX,et al.Study on chemical constituents of Aletris spicata[J].Chin Tradit Herb Drugs(中草药)2013,44(7):812-815.
[6]	Bi ZM,Wang ZT,Xu LS,et al.Studies on chemical constituents of Pholidota yunnanensis[J].Chin J Chin Mater Med(中国中药杂志),2004,29(1):47-49.
[7]	Cheng J,Liang H,Wang Y,et al.Studies on chemical constituents from the stems of Spatholobus suberectus[J].Chin J Chin Mater Med(中国中药杂志),2003,28(12):1 153-1 154.
[8]	Wen CS,Jim MF,Yu SC.Labdanes from Cryptomeria japonica[J].Phytochemistry,1994,37(4):1 109-1 114.
[9]	Tong XG,Cheng YX.Chemical constituents from Acorus tatarinowii[J].Nat Prod Res Dev(天然产物研究与开发),2011,23(3):404-409.
[10]	He ZH,Luo YG,Li HJ,et al.Chemical study on Porandra scandens[J].Nat Prod Res Dev(天然产物研究与开发),2006,18(2):238-242.