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毛菊苣中一个新的黄酮苷化合物

翁馨, 黄敏洁, 娄云云, 尚靖, 张健, 殷志琦

翁馨, 黄敏洁, 娄云云, 尚靖, 张健, 殷志琦. 毛菊苣中一个新的黄酮苷化合物[J]. 中国药科大学学报, 2020, 51(1): 29-32. DOI: 10.11665/j.issn.1000-5048.20200105
引用本文: 翁馨, 黄敏洁, 娄云云, 尚靖, 张健, 殷志琦. 毛菊苣中一个新的黄酮苷化合物[J]. 中国药科大学学报, 2020, 51(1): 29-32. DOI: 10.11665/j.issn.1000-5048.20200105
WENG Xin, HUANG Minjie, LOU Yunyun, SHANG Jing, ZHANG Jian, YIN Zhiqi. A new flavonoid glycoside from Cichorium glandulosum[J]. Journal of China Pharmaceutical University, 2020, 51(1): 29-32. DOI: 10.11665/j.issn.1000-5048.20200105
Citation: WENG Xin, HUANG Minjie, LOU Yunyun, SHANG Jing, ZHANG Jian, YIN Zhiqi. A new flavonoid glycoside from Cichorium glandulosum[J]. Journal of China Pharmaceutical University, 2020, 51(1): 29-32. DOI: 10.11665/j.issn.1000-5048.20200105

毛菊苣中一个新的黄酮苷化合物

基金项目: 国家“重大新药创制”科技重大专项资助项目(No.2019ZX09301156)

A new flavonoid glycoside from Cichorium glandulosum

  • 摘要: 对毛菊苣(Cichorium glandulosum Boiss.et Huet)地上部分的化学成分进行研究。采用硅胶、Sephadex LH-20、ODS柱色谱、半制备高效液相等多种方法进行分离纯化,通过理化性质及光谱数据对化合物进行结构鉴定。从中分离得到一个新的黄酮苷化合物,鉴定为槲皮素-3-O-[6″-O-(3-乙氧基-1,3-二氧代丙基)]-β-D-吡喃葡糖苷( 1 )。
    Abstract: Chemical constituents from the air dried parts of Cichorium glandulosum were studied. The chemical constituents of C. glandulosum were separated and purified by means of silica gel, Sephadex-LH 20, ODS column chromatography and semi-preparative high performance liquid chromatography. The structure was elucidated by physicochemical characteristics and spectral data. One new flavonoid glycoside was isolated from C. glandulosum, and identified as quercetin-3-O-[6″-O-(3-ethoxy-1, 3-dioxopropyl)]-β-D-glucopyranoside( 1 ).
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  • 刊出日期:  2020-02-24

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