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XIAO Yue, YUAN Shuai, LUO Ruxin, et al. Research progress on quality control methods for monitoring illicit drugs use in wastewater[J]. J China Pharm Univ, 2025, 56(2): 139 − 147. DOI: 10.11665/j.issn.1000-5048.2024051401
Citation: XIAO Yue, YUAN Shuai, LUO Ruxin, et al. Research progress on quality control methods for monitoring illicit drugs use in wastewater[J]. J China Pharm Univ, 2025, 56(2): 139 − 147. DOI: 10.11665/j.issn.1000-5048.2024051401
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Research progress on quality control methods for monitoring illicit drugs use in wastewater

  • 1.

    Academy of Forensic Science, Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai 200063

  • 2.

    School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China

Funds: This study was supported by the National Key Research and Development Program of China (2022YFC3300903), the Shanghai Key Laboratory of Forensic Medicine (21DZ2270800) and the Shanghai Forensic Service Platform (19DZ2292700)
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  • Received Date: May 13, 2024
    Graphical Abstract
    • Abstract

  • The use of wastewater analysis, or wastewater-based epidemiology, to assess and monitor the situation of drug abuse is now widely used at home and abroad. However, there is currently a lack of effective evaluation methods and effective ways of comparison, supervision and standardization, which is not conducive to the analysis and comparisons of data in different countries and regions. Quality control techniques can control the laboratory's analytical errors, safeguard the consistency and comparability of identification conclusions, and promote the further improvement of the level and capacity of urban drug governance, thus playing significant roles. This paper provides an overview of sample collection, sample preservation and transportation, laboratory analysis, back-calculation of drug use and external laboratory quality control in the process of wastewater analysis, with a view to exploring more comprehensive scientific and objective methods and approaches suitable for examining and evaluating qualitative and quantitative analysis of drugs in wastewater among laboratories.

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