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SONG Jiemei, WEN Xiaoan, SUN Hongbin. Progress in pathogenesis and therapeutic drugs of pulmonary arterial hypertension[J]. Journal of China Pharmaceutical University, 2013, 44(1): 1-10. DOI: 10.11665/j.issn.1000-5048.20130101
Citation: SONG Jiemei, WEN Xiaoan, SUN Hongbin. Progress in pathogenesis and therapeutic drugs of pulmonary arterial hypertension[J]. Journal of China Pharmaceutical University, 2013, 44(1): 1-10. DOI: 10.11665/j.issn.1000-5048.20130101

Progress in pathogenesis and therapeutic drugs of pulmonary arterial hypertension

  • Pulmonary arterial hypertension(PAH) is a progressive and fatal disease,characterized by elevated pulmonary vascular resistance and pulmonary arterial pressure,most often resulting in right-sided heart failure.The mechanisms of action,approved PAH therapies and the latest agents in late-stage clinical development were reviewed and described in this paper.
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