Chemical constituents from the exopleura of Ginkgo biloba and inhibition test of total ginkgolic acids against phytopathogenic fungi

Nine compounds were isolated from the exopleura of Ginkgo biloba. Their structures were elucidated by spectral analysis and chemical evidences as ginnol( 1 ), palmitone( 2 ), β-sitosterol( 3 ), stigmast-3, 6-dione( 4) , stigmast-4-ene-3, 6-dione( 5 ), ginkgolic acid( 6 ), ginkgoneolic acid( 7 ), triacotanoic acid( 8 )and ginkgonine( 9 ). Compounds 2-5 and 7-9 were isolated from the exopleura of Ginkgo biloba for the first time. Compounds 7 and 9 were novel natural products. The inhibition test against phytopathogenic fungi showed that total ginkgolic acids from the exopleura of Ginkgo biloba had strong anti-fungal activity.