A new norlignan from Saururus chinensis
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Abstract
A new norlignan, named sauchinolide A( 1 ), together with two known tetrahydrofuran lignans( 2 and 3 ), were isolated from the 95% EtOH extract of the whole plants of Saururus chinensis. All of them were isolated from the family Saururaceae for the first time. The effect of the obtained compounds on hypoxia/reoxygenation(H/R)injury in human endothelial EA. hy926 cells were preliminarily evaluated. The results showed that compound 2 exhibited moderate protective effect against H/R injury in EA. hy926.
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