Advances in the research on DT-13, a saponin of Liriope muscari(Decne)Baily

Liriope Muscari ［Liriope Muscari(Decne)Baily］, one of the original plant-loading varieties of Radix Liriopes included in “China Pharmacopoeia”(2010 ed), has various effects such as nourishing yin and promoting the secretion of body fluid, moistening lung and clearing away the heart-fire with the dried root. The saponin, DT-13, is the major active constituent of Liriope tuberous root, with a variety of pharmacological activities including anti-tumor metastasis, enhancing immunity, and anti-inflammation. In this paper, the chemical structure, content determination, pharmacological activities and safety evaluation of DT-13 were summarized. It suggests that DT-13 could be considered as a candidate drug with important research potentials and various promising application.