Citation: | XU Meng, GE Zhixin, HAO Meixi, ZHANG Can. Synthesis and in vitro biological activity of 3-phenyl-3-pyrrolylpentane derivatives[J]. Journal of China Pharmaceutical University, 2016, 47(1): 30-37. DOI: 10.11665/j.issn.1000-5048.20160104 |
[1] |
Haussler MR,Whitfield GK,Kaneko I,et al.Molecular mechanisms of vitamin D action[J].Calcif Tissue Int,2013,92(2):77-98.
|
[2] |
Bikle DD.Vitamin D metabolism,mechanism of action,and clinical applications[J].Chem Biol,2014,21(3):319-329.
|
[3] |
Feldman D,Krishnan AV,Swami S,et al.The role of vitamin D in reducing cancer risk and progression[J].Nat Rev Cancer,2014,14(5):342-357.
|
[4] |
Deeb KK,Trump DL,Johnson CS.Vitamin D signalling pathways in cancer:potential for anticancertherapeutics[J].Nat Rev Cancer,2007,7(9):684-700.
|
[5] |
Yamada S,Makishima M.Structure-activity relationship of nonsecosteroidal vitamin D receptormodulators[J].Trends Pharmacol Sci,2014,35(7):324-337.
|
[6] |
Boehm MF, Fitzgerald P, Zou A, et al. Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3[J].Chem Biol,1999,6(5):265-275.
|
[7] |
Konno K,Maki S,Fujishima T,et al.A novel and practical route to A-ring enyne synthon for 1 alpha,25-dihydroxyvitamin D3 analogs:synthesis of A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D2 and 3-methyl-1,25-dihydroxyvitamin D3[J].Bioorg Med Chem Lett,1998,8(2):151-156.
|
[8] |
Ciesielski F, Sato Y, Chebaro Y, et al. Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin D nuclear receptor[J].J Med Chem,2012,55(19):8440-8449.
|
[9] |
Shen W,Xue J,Zhao Z,et al.Novel nonsecosteroidal VDR agonists with phenyl-pyrrolyl pentaneskeleton[J].Eur J Med Chem,2013,69:768-778.
|
[10] |
Garay E, Donnelly R, Wang X, et al. Resistance to 1,25D-induced differentiation in human acute myeloid leukemia HL60-40AF cells is associated with reduced transcriptional activity and nuclear localization of the vitamin D receptor[J].J Cell Physiol,2007,213(3):816-825.
|
[11] |
Akhter J,Lu Y,Finlay I,et al.1α,25-Dihydroxyvitamin D 3 and its analogues,EB1089 and CB1093,profoundly inhibit the in vitro proliferation of the human hepatoblastoma cell line HepG2[J].ANZ J Surg,2001,71(7):414-417.
|
[1] | WANG Liming, JIANG Xiaomeng, GAO Yue, MA Yuxiao, ZENG Aizhong, GUO Wei. rhIL23R-CHR/Fc fusion protein inhibits Act-HaCaT inflammation and proliferation by downregulating ENST00000522718[J]. Journal of China Pharmaceutical University, 2022, 53(6): 734-741. DOI: 10.11665/j.issn.1000-5048.20220613 |
[2] | YUSUPUWAJIMU Alimujiang, AIZITIAILI Aihaiti, MOURBOUL Ablise, YANG Zheng, SAILIKEALA Alihan, LIU Zhengye. Design, synthesis and anti-cervical cancer activity of novel trifluoromethyl chalcones derivatives[J]. Journal of China Pharmaceutical University, 2022, 53(6): 674-684. DOI: 10.11665/j.issn.1000-5048.20220605 |
[3] | SHI Zhengke, CHEN Peipei, ZHANG Yixuan, WEI Jie, DU Yanan, LIU Xiaoquan. Up-regulated miR-452-5p suppressed the expression of RORα and promoted the proliferation and migration of HCC cells[J]. Journal of China Pharmaceutical University, 2022, 53(3): 323-332. DOI: 10.11665/j.issn.1000-5048.20220310 |
[4] | LIU Xiaoqing, LIANG Shuang, LIU Yongjun, ZHANG Na. Progress of research on inhibition strategy of bromodomain-containing protein 4 and its application in tumor therapy[J]. Journal of China Pharmaceutical University, 2021, 52(3): 270-278. DOI: 10.11665/j.issn.1000-5048.20210302 |
[5] | LIU Meishuo, WANG Haina, LONG Feida, LENG Nan, YANG Yongliang. Screening of a novel CRM1 targeting inhibitor and its effects on the proliferation and growth of extranodal NK/T cell lymphoma[J]. Journal of China Pharmaceutical University, 2020, 51(1): 44-51. DOI: 10.11665/j.issn.1000-5048.20200108 |
[6] | LUO Chunxia, ZHU Li, LI Xinyu, AMET Mutallip, NIJIATI Yiliyaer, LI Xinxia, GUAN Ming. Synthesis of folic acid-alliinase conjugate and its in situ inhibition of tumor cell proliferation by combination of alliin[J]. Journal of China Pharmaceutical University, 2019, 50(6): 721-727. DOI: 10.11665/j.issn.1000-5048.20190613 |
[7] | WANG Jiaqi, CHEN Jiao, SUN Xiaoyan, LU Wuguang, YANG Yang, CAI Xueting, WANG Xiao-ning, CAO Peng. A mechanism research of novel inhibitor of PAK1 inducing colorectal cancer DLD-1 apoptosis[J]. Journal of China Pharmaceutical University, 2018, 49(2): 229-237. DOI: 10.11665/j.issn.1000-5048.20180214 |
[8] | CHEN Jiajia, BEI Yuncheng, ZHANG Dongmei, SHEN Pingping. Combination of artemether with etoposide inhibits cell proliferation and invasion in small cell lung cancer cell line H446[J]. Journal of China Pharmaceutical University, 2017, 48(2): 201-207. DOI: 10.11665/j.issn.1000-5048.20170211 |
[9] | SHEN Yanli, JI Xiaonan, GAO Xiangdong. Combination of scFv-AFP with doxorubicin inhibits cell proliferation in hepatocellular carcinoma cell Huh7[J]. Journal of China Pharmaceutical University, 2016, 47(1): 101-105. DOI: 10.11665/j.issn.1000-5048.20160115 |
[10] | WANG Zhenghua, LIANG Tong, LI Tao, ZHOU Keyuan. Effect of chrysin in inhibiting proliferation of human nasopharyngeal carcinoma cell line CNE-2[J]. Journal of China Pharmaceutical University, 2013, 44(1): 93-96. DOI: 10.11665/j.issn.1000-5048.20130116 |