LIU Zongliang, ZHANG Renmei, MENG Qingguo. Advances of targeting heat shock protein 70 drugs[J]. Journal of China Pharmaceutical University, 2017, 48(4): 416-424. DOI: 10.11665/j.issn.1000-5048.20170405
Citation:
LIU Zongliang, ZHANG Renmei, MENG Qingguo. Advances of targeting heat shock protein 70 drugs[J]. Journal of China Pharmaceutical University, 2017, 48(4): 416-424. DOI: 10.11665/j.issn.1000-5048.20170405
LIU Zongliang, ZHANG Renmei, MENG Qingguo. Advances of targeting heat shock protein 70 drugs[J]. Journal of China Pharmaceutical University, 2017, 48(4): 416-424. DOI: 10.11665/j.issn.1000-5048.20170405
Citation:
LIU Zongliang, ZHANG Renmei, MENG Qingguo. Advances of targeting heat shock protein 70 drugs[J]. Journal of China Pharmaceutical University, 2017, 48(4): 416-424. DOI: 10.11665/j.issn.1000-5048.20170405
Heat shock protein 70(HSP70)family is one ofthe most conserved proteinin evolutionand plays critical, role in proteostasis. HSP70 is becoming an interesting target for multiple diseases such as cancer and Alzheimer′s disease. There are many drugs targeted to HSP70 in preclinical study. In this review, the classification, the structure, the function of HSP70, and the drugs of the HSP70 family are reviewed.
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