One new diterpenoid alkaloid from<i> Aconitum carmichaeli</i>

FANG Daqing; LIU Fang; ZHANG Sijia; CAI Chaoqun; LIU Minzhuo; LIU Jinghan; YANG Chunhua; WANG Hao

doi:10.11665/j.issn.1000-5048.20170510

FANG Daqing, LIU Fang, ZHANG Sijia, CAI Chaoqun, LIU Minzhuo, LIU Jinghan, YANG Chunhua, WANG Hao. One new diterpenoid alkaloid from Aconitum carmichaeli[J]. Journal of China Pharmaceutical University, 2017, 48(5): 568-571. DOI: 10.11665/j.issn.1000-5048.20170510

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One new diterpenoid alkaloid from Aconitum carmichaeli

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Four compounds were isolated from the lateral roots of Aconitum carmichaeli by Al₂O₃, silica gel and preparative HPLC. Their structures were identified as: (13R, 15S, 19S)-13, 15, 19-triol-hetisan( 1 ), fuziline( 2 ), neoline( 3 )and beiwutine( 4 ), by methods of NMR, MS spectroscopy as well as single crystal X-ray crystallography. Among them, compound 1 was considered as a new diterpenoid alkaloid.

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One new diterpenoid alkaloid from Aconitum carmichaeli

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